Catalog Number:

RA20002

Product Type:

Polyclonal antiserum

Immunogen Sequence:

FMRFamide

Host:

Rabbit

Reactivity:

Rat, Mouse

Applications:

Immunocytochemistry, Immunohistochemistry

Description:

Phe Met Arg Phe-NH2, a tetrapeptide neurotransmitter, a member of the same family of RFamide peptides as FLRFamide, sharing the same C terminal RFamide sequence.

FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL Gene encodes a preproprotein where upon cleavage forms two active peptides possessing similar function.

Reference:

Perry, S. J.; Yi-Kung Huang, E.; Cronk, D.; Bagust, J.; Sharma, R.; Walker, R. J.; Wilson, S.; Burke, J. F. : A human gene encoding morphine modulating peptides related to NPFF and FMRFamide. FEBS Lett. 409: 426-430, 1997.