Catalog Number:

GT15074

Product Type:

Affinity purified

Immunogen Sequence:

Recombinant chicken TGF beta 3

Host:

Goat

Reactivity:

Human, Chicken

Applications:

Immunohistochemistry on paraffin embedded sections, ELISA, Western Blot

Description:

Transforming Growth Factor beta 3 (TGF beta 3) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional, capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide.

Reference:

Clark DA, Coker R. Transforming growth factor-beta (TGF-beta). Int J Biochem Cell Biol. 1998 Mar;30(3):293-8.

Cox DA. Transforming growth factor-beta 3. Cell Biol Int. 1995 May;19(5):357-71.

Lui WY, Lee WM, Cheng CY. TGF-betas: their role in testicular function and Sertoli cell tight junction dynamics. Int J Androl. 2003 Jun;26(3):147-60.

Anchan RM, Reh TA. Transforming growth factor-beta-3 is mitogenic for rat retinal progenitor cells in vitro. J Neurobiol. 1995 Oct;28(2):133-45.