Catalog Number:

GT15053

Product Type:

Affinity Purified

Immunogen Sequence:

Recombinant human BMP-2

Host:

Goat

Reactivity:

Human, Rat

Applications:

Immunocytochemistry, Immunoghistochemistry,
Western Blot, ELISA

Description:

Bone Morphogenic Proteins (BMP) are members of the TGF-beta superfamily that affect bone and cartilage formation (Hogan 1996, Reddi 1998 and Francis-West et al. 1999). Mature BMPs are 30-38 kDa proteins that assume a TGF-beta -like cysteine knot configuration.

Reference:

Francis-West PH et al. BMP/GDF-signalling interactions during synovial joint development. Cell Tissue Res 296:111-9 (1999).

Mundy G et al. Stimulation of bone formation in vitro and in rodents by statins. Science 286:1946-9 (1999).

Macias D et al. Regulation by members of the transforming growth factor beta superfamily of the digital and interdigital fates of the autopodial limb mesoderm. Cell Tissue Res 296:95-102 (1999).