Catalog Number:

GT15044

Product Type:

Affinity purified

Immunogen Sequence:

Recombinant humanCaspase-3 zymogen

Host:

Goat

Reactivity:

Human

Applications:

Immunoprecipitation, Western Blot

Description:

Caspase 3 is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants which encode the same protein.

Reference:

Krajewska M et al. Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease. Cancer Res 57:1605-13 (1997).