Catalog Number:

GT15042

Product Type:

Affinity purified

Immunogen Sequence:

Recombinant mouse Cathepsin D

Host:

Goat

Reactivity:

Mouse, Human

Applications:

Immunohistochemistry, Western Blot, ELISA

Description:

Cathepsin D is one of the lysosomal proteinases. Cathepsin D has been reported to be involved in malignant tumour progression and with prognosis of various human cancers.

Reference:

Faust, P. L.; Kornfeld, S.; Chirgwin, J. M. :
Cloning and sequence analysis of cDNA for human cathepsin D. Proc. Nat. Acad. Sci. 82: 4910-4914, 1985.

Tyynela, J.; Sohar, I.; Sleat, D. E.; Gin, R. M.; Donnelly, R. J.; Baumann, M.; Haltia, M.; Lobel, P. :
A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration. EMBO J. 19: 2786-2792, 2000.