The
hypothalamic agouti-related protein (AGRP) regulates body
weight via central melanocortin receptors. The agouti gene
in mice encodes a cell-signaling protein that acts as an
antagonist at the melanocortin-1 receptor (MC1R).
Reference:
Naeve,
G. S.; Ramakrishnan, M.; Kramer, R.; Hevroni, D.; Citri,
Y.; Theill, L. E. :
Neuritin: a gene induced by neural activity and neurotrophins
that promotes neuritogenesis. Proc. Nat. Acad. Sci. 94: 2648-2653,
1997.