Catalog Number:

GT15034

Product Type:

Affinity purified

Immunogen Sequence:

Recombinant mouse Wnt-5a peptide containing amino acid residues Gln 254 - Cys 334 of mouse Wnt-5a

Host:

Goat

Reactivity:

Rat, Mouse

Applications:

Immunohistochemistry, Western Blot, ELISA

Description:

The WNT gene family consists of structurally related genes that encode cysteine-rich secreted glycoproteins that act as extracellular signaling factors.

Reference:

Clark, C. C.; Cohen, I.; Eichstetter, I.; Cannizzaro, L. A.; McPherson, J. D.; Wasmuth, J. J.; Iozzo, R. V. : Molecular cloning of the human proto-oncogene Wnt-5A and mapping of the gene (WNT5A) to chromosome 3p14-p21. Genomics 18: 249-260, 1993.

Gavin, B. J.; McMahon, J. A.; McMahon, A. P. : Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 4: 2319-2332, 1990.

He, X.; Saint-Jeannet, J.-P.; Wang, Y.; Nathans, J.; Dawid, I.; Varmus, H. : A member of the frizzled protein family mediating axis induction by Wnt-5A. Science 275: 1652-1654, 1997.