Catalog Number:

GT15033

Product Type:

Affinity purified

Immunogen Sequence:

Recombinant mouse Wnt-4 peptide consisting of amino acid residues 37 - 76 and 222 – 295 joined by a linker (GGGGSGGGGSGGGGS). The polypeptide also has six histidine residues added at the carboxy-terminus

Host:

Goat

Reactivity:

Rat, Mouse

Applications:

Immunohistochemistry, Western Blot, ELISA

Description:

The WNT gene family consists of structurally related genes that encode cysteine-rich secreted glycoproteins that act as extracellular signaling factors.

Reference:

Brisken, C.; Heineman, A.; Chavarria, T.; Elenbaas, B.; Tan, J.; Dey, S. K.; McMahon, J. A.; McMahon, A. P.; Weinberg, R. A. : Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev. 14: 650-654, 2000.

Jordan, B. K.; Mohammed, M.; Ching, S. T.; Delot, E.; Chen, X.-N.; Dewing, P.; Swain, A.; Rao, P. N.; Elejalde, B. R.; Vilain, E. : Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans. Am. J. Hum. Genet.