Catalog Number:

GT15023

Product Type:

Affinity Purified Goat IgG

Immunogen Sequence:

recombinant mouse Agouti-Related Protein

Host:

Goat

Reactivity:

Mouse, Rat

Applications:

Immunohistochemistry, Immunocytochemistry, Western Blot, ELISA

Description:

The hypothalamic agouti-related protein (AGRP) regulates body weight via central melanocortin receptors. The agouti gene in mice encodes a cell-signaling protein that acts as an antagonist at the melanocortin-1 receptor (MC1R).

Reference:

Naeve, G. S.; Ramakrishnan, M.; Kramer, R.; Hevroni, D.; Citri, Y.; Theill, L. E. : Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis. Proc. Nat. Acad. Sci. 94: 2648-2653, 1997.