Catalog Number:

GT15022

Product Type:

Affinity Purified Goat IgG

Immunogen Sequence:

recombinant mouse - neuregulin-3 EGF-like domain (aa284-344)

Host:

Goat

Reactivity:

Mouse

Applications:

Immunohistochemistry, Immunocytochemistry,
Western Blot, ELISA

Description:

Neuritin is a glutamate and neurotrophin receptor target gene encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth. neuritin is induced by neural activity and by the activity-regulated neurotrophins BDNF and NTF3. Recombinant studies showed that neuritin is a GPI-anchored protein that promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.

Reference:

Naeve, G. S.; Ramakrishnan, M.; Kramer, R.; Hevroni, D.; Citri, Y.; Theill, L. E. : Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis. Proc. Nat. Acad. Sci. 94: 2648-2653, 1997.