Catalog Number:

GT15000

Product Type:

Affinity Purified Goat IgG

Immunogen Sequence:

Recombinant human neurotrophin 3

Host:

Goat

Reactivity:

Rat , Human

Applications:

Immunohistochemistry, Western Blotting , ELISA

Description:

NTF3 promotes the survival of, and induces neurite outgrowth from, a subset of neural crest and placode-derived neurons. It regulates the proliferation of cultured neural crest progenitor cells grown in a serum-free defined medium.
The arrest of dorsal root axonal regeneration at the transitional zone between the peripheral and central nervous system has been repeatedly described.

Reference:

Hattori, M.; Kuwata, S.; Fukuda, R.; Sasaki, T.; Shibata, Y.; Kazamatsuri, H.; Nanko, S. :
Dinucleotide repeat polymorphism in the promoter region of neurotrophin-3 gene (NT3). Hum. Molec. Genet. 2: 1511 only, 1993.