Catalog Number:

GP10109

Product Type:

Antibody

Immunogen Sequence:

QEDPNAYSEEFFDV - Corresponding to residues 232-245 of guinea pig proDynorphin

Host:

Guinea Pig

Reactivity:

Guinea Pig

Applications:

Immunohistochemistry 1:500

Description:

Dynorphin peptides are members of the opioid peptide family and contain the canonical opioid sequence Tyr-Gly-Gly-Phe. These peptides are derived from prodynorphin and include dynorphin A, dynorphin B and alpha neo-endorphin. Of the opioid peptides, the dynorphins have the highest affinity for the kappa opioid receptor. They are found distributed throughout the nervous system and play a role in many physiological functions.

Reference:

Yuferov, V.P., Laforge, K. S., Spangler, R., Maggos, C. E., and Kreek, M. J. (1996). Guinea pig preprodynorphin mRNA: primary structure and regional quantitation in the brain. DNA Cell Biol 15, 1105-12.