Catalog Number:

CH15000

Product Type:

Antibody

Immunogen Sequence:

Recombinant human brainderived neurotrophic factor

Host:

Chicken

Reactivity:

Rat, Human

Applications:

Immunohistochemistry, Western Blot, ELISA

Description:

Brain-derived neurotrophic factor is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain.

Reference:

Baker-Herman, T. L.; Fuller, D. D.; Bavis, R. W.; Zabka, A. G.; Golder, F. J.; Doperalski, N. J.; Johnson, R. A.; Watters, J. J.; Mitchell, G. S. : BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia. Nature Neurosci. 7: 48-55, 2004.

Hanson, I. M.; Seawright, A.; van Heyningen, V. : The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13-p14. Genomics 13: 1331-1333, 1992.

Hofer, M. M.; Barde, Y.-A. : Brain-derived neurotrophic factor prevents neuronal death in vivo. Nature 331: 261-262, 1988.